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課程概述 |
Metabolomics is well accepted as a truly translational tool for precision medicine nowadays. Among other techniques, NMR spectroscopy has become a promising and reliable approach that is able to analyze disease related metabolism for a decade. In this new elective course, we proposed to deliver lectures covering a few topics, including basics of NMR spectroscopy (4 hr), detection and analyses of low molecular weight metabolites in human urine and serum samples (8 hr), application to various disease diagnoses (cancer, diabetes, cardiovascular and neurodegenerative diseases) (8 hr), as well as hand-on practice (4 hr) in Biopark NMR lab, see course syllabus. Lecturers include: Prof. M-S Hsiao (previous National Yang Ming Chiao Tung University faculty), Prof. D-L Tzou (IoC, AS), Dr. C-K Chang (Taiwan Biobank) and Dr. Y-C Lou (BioTReC, AS). |
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課程目標 |
? Familiar with basics of NMR spectroscopy
? How to assign the NMR signals for urine and serum samples
? What are the information can be extracted from the NMR signals
? Introduction to in vitro diagnosis report (IVDr)
? How to analyze the information for profiling and diagnosis
? Applications NMR spectroscopy-based metabolomics to various diseases, including cancers, diabetes, cardiovascular and neurodegenerative diseases
? Hand-on practice experience
At the end of the course, students will take NMR measurement of urine sample by themselves and conduct an official IVDr, while using their urine samples for example. |